A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses

Surface antigens of pathogens are commonly targeted by vaccine-elicited antibodies but antigenic variability, notably in RNA viruses such as influenza, HIV and SARS-CoV-2, pose challenges for control by vaccination. For example, influenza A(H3N2) entered the human population in 1968 causing a pandem...

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Detalles Bibliográficos
Autores principales: Harvey, William T., Davies, Vinny, Daniels, Rodney S., Whittaker, Lynne, Gregory, Victoria, Hay, Alan J., Husmeier, Dirk, McCauley, John W., Reeve, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079231/
https://www.ncbi.nlm.nih.gov/pubmed/36972311
http://dx.doi.org/10.1371/journal.pcbi.1010885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079231/
https://www.ncbi.nlm.nih.gov/pubmed/36972311
http://dx.doi.org/10.1371/journal.pcbi.1010885

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