Allele-dependent interaction of LRRK2 and NOD2 in leprosy

Leprosy, caused by Mycobacterium leprae, rarely affects children younger than 5 years. Here, we studied a multiplex leprosy family that included monozygotic twins aged 22 months suffering from paucibacillary leprosy. Whole genome sequencing identified three amino acid mutations previously associated...

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Detalles Bibliográficos
Autores principales: Dallmann-Sauer, Monica, Xu, Yong Zhong, da Costa, Ana Lúcia França, Tao, Shao, Gomes, Tiago Araujo, Prata, Rhana Berto da Silva, Correa-Macedo, Wilian, Manry, Jérémy, Alcaïs, Alexandre, Abel, Laurent, Cobat, Aurélie, Fava, Vinicius M., Pinheiro, Roberta Olmo, Lara, Flavio Alves, Probst, Christian M., Mira, Marcelo T., Schurr, Erwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079233/
https://www.ncbi.nlm.nih.gov/pubmed/36972292
http://dx.doi.org/10.1371/journal.ppat.1011260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079233/
https://www.ncbi.nlm.nih.gov/pubmed/36972292
http://dx.doi.org/10.1371/journal.ppat.1011260

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