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circNFXL1 Modulates the Kv2.1 Channel Function in Hypoxic Human Pulmonary Artery Smooth Muscle Cells via Sponging miR-29b-2-5p as a Competitive Endogenous RNA

Pulmonary arterial hypertension is characterized by abnormal pulmonary vasoconstriction and vascular remodeling caused by the dysregulation of K(+) channels in PA smooth muscle cells (PASMCs). However, how the K(+) channels are dysregulated is still unclear. Circular RNAs (circRNAs) are noncoding RN...

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Detalles Bibliográficos
Autores principales: Li, Shan-Shan, Liang, Shuang, Li, Lu, Yang, Houzhi, Long, Yao, Zhuo, Donghai, Chen, Xu, Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079296/
https://www.ncbi.nlm.nih.gov/pubmed/36651941
http://dx.doi.org/10.1097/FJC.0000000000001396