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An expectation–maximization framework for comprehensive prediction of isoform-specific functions

MOTIVATION: Advances in RNA sequencing technologies have achieved an unprecedented accuracy in the quantification of mRNA isoforms, but our knowledge of isoform-specific functions has lagged behind. There is a need to understand the functional consequences of differential splicing, which could be su...

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Detalles Bibliográficos
Autores principales: Karlebach, Guy, Carmody, Leigh, Sundaramurthi, Jagadish Chandrabose, Casiraghi, Elena, Hansen, Peter, Reese, Justin, Mungall, Christopher J, Valentini, Giorgio, Robinson, Peter N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079350/
https://www.ncbi.nlm.nih.gov/pubmed/36929917
http://dx.doi.org/10.1093/bioinformatics/btad132