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An expectation–maximization framework for comprehensive prediction of isoform-specific functions
MOTIVATION: Advances in RNA sequencing technologies have achieved an unprecedented accuracy in the quantification of mRNA isoforms, but our knowledge of isoform-specific functions has lagged behind. There is a need to understand the functional consequences of differential splicing, which could be su...
Autores principales: | Karlebach, Guy, Carmody, Leigh, Sundaramurthi, Jagadish Chandrabose, Casiraghi, Elena, Hansen, Peter, Reese, Justin, Mungall, Christopher J, Valentini, Giorgio, Robinson, Peter N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079350/ https://www.ncbi.nlm.nih.gov/pubmed/36929917 http://dx.doi.org/10.1093/bioinformatics/btad132 |
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