Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy

Human bone marrow-derived mesenchymal stem cells (hBMSCs) are promising candidates for stem cell therapy in clinical trials. Applications of hBMSCs in clinical therapy are limited by cellular senescence due to long-term ex vivo expansion. Metformin, an oral hypoglycemic drug for type 2 diabetes, has...

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Detalles Bibliográficos
Autores principales: Ye, Pingting, Feng, Lei, Zhang, Dan, Li, Ruihao, Wen, Yixuan, Tong, Xiaohan, Shi, Shuo, Dong, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079386/
https://www.ncbi.nlm.nih.gov/pubmed/37035446
http://dx.doi.org/10.1155/2023/1429642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079386/
https://www.ncbi.nlm.nih.gov/pubmed/37035446
http://dx.doi.org/10.1155/2023/1429642

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