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KCa3.1 Promotes Proinflammatory Exosome Secretion by Activating AKT/Rab27a in Atrial Myocytes during Rapid Pacing

PURPOSE: The aim of this study was to investigate the role of the medium-conductance calcium-activated potassium channel (KCNN4, KCa3.1) in the secretion of proinflammatory exosomes by atrial myocytes. METHODS: Eighteen beagles were randomly divided into the sham group (n = 6), pacing group (n = 6),...

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Detalles Bibliográficos
Autores principales: Liu, Dishiwen, Chen, Huiyu, Fu, Yuntao, Yao, Yajun, He, Shanqing, Wang, Youcheng, Cao, Zhen, Wang, Xuewen, Yang, Mei, Zhao, Qingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079387/
https://www.ncbi.nlm.nih.gov/pubmed/37035755
http://dx.doi.org/10.1155/2023/3939360