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Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial

BACKGROUND: Whole sporozoite immunization under chemoprophylaxis (CPS regime) induces long-lasting sterile homologous protection in the controlled human malaria infection model using Plasmodium falciparum strain NF54. The relative proficiency of liver-stage parasite development may be an important f...

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Detalles Bibliográficos
Autores principales: van der Boor, Saskia C., Alkema, Manon, van Gemert, Geert-Jan, Teelen, Karina, van de Vegte-Bolmer, Marga, Walk, Jona, van Crevel, Reinout, de Mast, Quirijn, Ockenhouse, Christian F., Sauerwein, Robert W., McCall, Matthew B. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079489/
https://www.ncbi.nlm.nih.gov/pubmed/37024868
http://dx.doi.org/10.1186/s12916-023-02788-9