Prion infection modulates hematopoietic stem/progenitor cell fate through cell-autonomous and non-autonomous mechanisms

Studies of PrP(C)-derived prion disease generally focus on neurodegeneration. However, little is known regarding the modulation of hematopoietic stem progenitor cells (HSPCs) that express PrP(C) in prion infection. Among bone marrow (BM) hematopoietic cells, hematopoietic stem cells (HSCs) strongly...

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Detalles Bibliográficos
Autores principales: Sim, Hyun-Jaung, Kim, Yong-Chan, Bhattarai, Govinda, Won, Sae-Young, Lee, Jeong-Chae, Jeong, Byung-Hoon, Kook, Sung-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079512/
https://www.ncbi.nlm.nih.gov/pubmed/36707620
http://dx.doi.org/10.1038/s41375-023-01828-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079512/
https://www.ncbi.nlm.nih.gov/pubmed/36707620
http://dx.doi.org/10.1038/s41375-023-01828-w

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