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Prion infection modulates hematopoietic stem/progenitor cell fate through cell-autonomous and non-autonomous mechanisms
Studies of PrP(C)-derived prion disease generally focus on neurodegeneration. However, little is known regarding the modulation of hematopoietic stem progenitor cells (HSPCs) that express PrP(C) in prion infection. Among bone marrow (BM) hematopoietic cells, hematopoietic stem cells (HSCs) strongly...
Autores principales: | Sim, Hyun-Jaung, Kim, Yong-Chan, Bhattarai, Govinda, Won, Sae-Young, Lee, Jeong-Chae, Jeong, Byung-Hoon, Kook, Sung-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079512/ https://www.ncbi.nlm.nih.gov/pubmed/36707620 http://dx.doi.org/10.1038/s41375-023-01828-w |
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