Cognitive impairments correlate with increased central nervous system immune activation after allogeneic haematopoietic stem cell transplantation

Murine studies indicate that, after allogeneic haematopoietic stem cell transplantation (aHSCT), donor-derived macrophages replace damaged microglia and alloreactive T-cells invade the central nervous system (CNS). The clinical relevance of this is unknown. We assessed CNS immune surveillance and me...

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Detalles Bibliográficos
Autores principales: Boberg, Erik, Kadri, Nadir, Hagey, Daniel W., Schwieler, Lilly, El Andaloussi, Samir, Erhardt, Sophie, Iacobaeus, Ellen, Le Blanc, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079537/
https://www.ncbi.nlm.nih.gov/pubmed/36792657
http://dx.doi.org/10.1038/s41375-023-01840-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079537/
https://www.ncbi.nlm.nih.gov/pubmed/36792657
http://dx.doi.org/10.1038/s41375-023-01840-0

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