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SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients

Patients with COVID-19 may develop abnormal inflammatory response, followed in some cases by severe disease and long-lasting syndromes. We show here that in vitro exposure to SARS-CoV-2 activates the expression of the human endogenous retrovirus (HERV) HERV-W proinflammatory envelope protein (ENV) i...

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Detalles Bibliográficos
Autores principales: Charvet, Benjamin, Brunel, Joanna, Pierquin, Justine, Iampietro, Mathieu, Decimo, Didier, Queruel, Nelly, Lucas, Alexandre, Encabo-Berzosa, María del Mar, Arenaz, Izaskun, Marmolejo, Tania Perez, Gonzalez, Arturo Ivan, Maldonado, Armando Castorena, Mathieu, Cyrille, Küry, Patrick, Flores-Rivera, Jose, Torres-Ruiz, Fernanda, Avila-Rios, Santiago, Salgado Montes de Oca, Gonzalo, Schoorlemmer, Jon, Perron, Hervé, Horvat, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079620/
https://www.ncbi.nlm.nih.gov/pubmed/37091988
http://dx.doi.org/10.1016/j.isci.2023.106604