A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness

Molecular mechanisms of glucose-stimulated insulin secretion (GSIS) from pancreatic β-cells are not fully understood. GSIS deteriorations are believed to underlie the pathogenesis of type 2 diabetes mellitus. By comparing transcript levels of 3 insulin secreting MIN6 cell sublines with strong glucos...

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Detalles Bibliográficos
Autores principales: Tanaka, Aya, Kosuda, Minami, Yamana, Midori, Furukawa, Asami, Nagasawa, Akiko, Fujishiro, Midori, Kohno, Genta, Ishihara, Hisamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079668/
https://www.ncbi.nlm.nih.gov/pubmed/37024560
http://dx.doi.org/10.1038/s41598-023-32589-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079668/
https://www.ncbi.nlm.nih.gov/pubmed/37024560
http://dx.doi.org/10.1038/s41598-023-32589-2

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