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A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness

Molecular mechanisms of glucose-stimulated insulin secretion (GSIS) from pancreatic β-cells are not fully understood. GSIS deteriorations are believed to underlie the pathogenesis of type 2 diabetes mellitus. By comparing transcript levels of 3 insulin secreting MIN6 cell sublines with strong glucos...

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Detalles Bibliográficos
Autores principales:	Tanaka, Aya, Kosuda, Minami, Yamana, Midori, Furukawa, Asami, Nagasawa, Akiko, Fujishiro, Midori, Kohno, Genta, Ishihara, Hisamitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079668/ https://www.ncbi.nlm.nih.gov/pubmed/37024560 http://dx.doi.org/10.1038/s41598-023-32589-2

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