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Construction of a synthetic metabolic pathway for biosynthesis of 2,4-dihydroxybutyric acid from ethylene glycol

Ethylene glycol is an attractive two-carbon alcohol substrate for biochemical product synthesis as it can be derived from CO(2) or syngas at no sacrifice to human food stocks. Here, we disclose a five-step synthetic metabolic pathway enabling the carbon-conserving biosynthesis of the versatile platf...

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Detalles Bibliográficos
Autores principales: Frazão, Cláudio J. R., Wagner, Nils, Rabe, Kenny, Walther, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079672/
https://www.ncbi.nlm.nih.gov/pubmed/37024485
http://dx.doi.org/10.1038/s41467-023-37558-x