DNA double-strand break end synapsis by DNA loop extrusion

DNA double-strand breaks (DSBs) occur every cell cycle and must be efficiently repaired. Non-homologous end joining (NHEJ) is the dominant pathway for DSB repair in G1-phase. The first step of NHEJ is to bring the two DSB ends back into proximity (synapsis). Although synapsis is generally assumed to...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jin H., Brandão, Hugo B., Hansen, Anders S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079674/
https://www.ncbi.nlm.nih.gov/pubmed/37024496
http://dx.doi.org/10.1038/s41467-023-37583-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079674/
https://www.ncbi.nlm.nih.gov/pubmed/37024496
http://dx.doi.org/10.1038/s41467-023-37583-w

Ejemplares similares