Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis

Wnt signaling is required to maintain bipotent progenitors for neural and paraxial mesoderm cells, the neuromesodermal progenitor (NMP) cells that reside in the epiblast and tailbud. Since epiblast/tailbud cells receive Wnt ligands produced by one another, this exchange may average out the heterogen...

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Detalles Bibliográficos
Autores principales: Hatakeyama, Yudai, Saito, Nen, Mii, Yusuke, Takada, Ritsuko, Shinozuka, Takuma, Takemoto, Tatsuya, Naoki, Honda, Takada, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079677/
https://www.ncbi.nlm.nih.gov/pubmed/37024462
http://dx.doi.org/10.1038/s41467-023-37350-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079677/
https://www.ncbi.nlm.nih.gov/pubmed/37024462
http://dx.doi.org/10.1038/s41467-023-37350-x

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