Experimental strategies to improve drug-target identification in mass spectrometry-based thermal stability assays

Mass spectrometry (MS)-based thermal stability assays have recently emerged as one of the most promising solutions for the identification of protein-ligand interactions. Here, we have investigated eight combinations of several recently introduced MS-based advancements, including the Phase-Constraine...

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Detalles Bibliográficos
Autores principales: Phaneuf, Clifford G., Aizikov, Konstantin, Grinfeld, Dmitry, Kreutzmann, Arne, Mourad, Daniel, Lange, Oliver, Dai, Daniel, Zhang, Bailin, Belenky, Alexei, Makarov, Alexander A., Ivanov, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079678/
https://www.ncbi.nlm.nih.gov/pubmed/37024568
http://dx.doi.org/10.1038/s42004-023-00861-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079678/
https://www.ncbi.nlm.nih.gov/pubmed/37024568
http://dx.doi.org/10.1038/s42004-023-00861-1

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