Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage

Parkinson’s Disease (PD) is a common neurodegenerative disorder affecting millions of people worldwide for which there are only symptomatic therapies. Small molecules able to target key pathological processes in PD have emerged as interesting options for modifying disease progression. We have previo...

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Detalles Bibliográficos
Autores principales: Rosado-Ramos, Rita, Poças, Gonçalo M., Marques, Daniela, Foito, Alexandre, M. Sevillano, David, Lopes-da-Silva, Mafalda, Gonçalves, Luís G., Menezes, Regina, Ottens, Marcel, Stewart, Derek, Ibáñez de Opakua, Alain, Zweckstetter, Markus, Seabra, Miguel C., Mendes, César S., Outeiro, Tiago Fleming, Domingos, Pedro M., Santos, Cláudia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079842/
https://www.ncbi.nlm.nih.gov/pubmed/37024503
http://dx.doi.org/10.1038/s41467-023-37561-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079842/
https://www.ncbi.nlm.nih.gov/pubmed/37024503
http://dx.doi.org/10.1038/s41467-023-37561-2

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