Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus

Generalized status epilepticus (SE) triggers a robust neuroinflammatory response involving reactive astrocytosis, activation of brain-resident microglia, and brain infiltration of CCR2+ monocytes. Multiple lines of evidence indicate that quenching SE-induced neuroinflammation can alleviate the adver...

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Detalles Bibliográficos
Autores principales: Alemán-Ruiz, Carlos, Wang, Wenyi, Dingledine, Ray, Varvel, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079855/
https://www.ncbi.nlm.nih.gov/pubmed/37024553
http://dx.doi.org/10.1038/s41598-023-32752-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079855/
https://www.ncbi.nlm.nih.gov/pubmed/37024553
http://dx.doi.org/10.1038/s41598-023-32752-9

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