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Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus
Generalized status epilepticus (SE) triggers a robust neuroinflammatory response involving reactive astrocytosis, activation of brain-resident microglia, and brain infiltration of CCR2+ monocytes. Multiple lines of evidence indicate that quenching SE-induced neuroinflammation can alleviate the adver...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079855/ https://www.ncbi.nlm.nih.gov/pubmed/37024553 http://dx.doi.org/10.1038/s41598-023-32752-9 |