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Combination treatment with FAAH inhibitors/URB597 and ferroptosis inducers significantly decreases the growth and metastasis of renal cell carcinoma cells via the PI3K-AKT signaling pathway

Ferroptosis, a nonapoptotic form of programmed cell death characterized by significant iron-dependent peroxidation of phospholipids, is regulated by cellular metabolism, redox homeostasis, and various cancer-related signaling pathways. Recently, considerable progress has been made in demonstrating t...

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Detalles Bibliográficos
Autores principales: Hao, Junfeng, Chen, Qiguang, Feng, Yongmin, Jiang, Qiyu, Sun, Huiwei, Deng, Botian, Huang, Xin, Guan, Jibin, Chen, Qiuping, Liu, Xincheng, Wang, Yanjin, Cao, Peng, Feng, Fan, Li, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079857/
https://www.ncbi.nlm.nih.gov/pubmed/37024452
http://dx.doi.org/10.1038/s41419-023-05779-z