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Ketorolac modulates Rac-1/HIF-1α/DDX3/β-catenin signalling via a tumor suppressor prostate apoptosis response-4 (Par-4) in renal cell carcinoma

Renal cell carcinoma (RCC) is the most difficult-to-treat form of kidney cancer with a median 5-year survival of 10% under metastatic setting. In RCC, although cytoreductive nephrectomy is common, approximately 20–30% of patients will develop recurrent cancer after surgery, which highlights the need...

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Detalles Bibliográficos
Autores principales: Sonawane, Vinay, Ghosalkar, Jeevan, Achrekar, Swati, Joshi, Kalpana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079967/
https://www.ncbi.nlm.nih.gov/pubmed/37024613
http://dx.doi.org/10.1038/s41598-023-32627-z