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The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway

When the proliferation of residual hepatocytes is prohibited, biliary epithelial cells (BECs) transdifferentiate into nascent hepatocytes to accomplish liver regeneration. Despite significant interest in transdifferentiation, little is known about the maintenance of nascent hepatocytes in post-injur...

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Detalles Bibliográficos
Autores principales: Song, Jingmei, Ma, Jianlong, Liu, Xing, Huang, Zhuofu, Li, Lianghui, Li, Linke, Luo, Lingfei, Ni, Rui, He, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079969/
https://www.ncbi.nlm.nih.gov/pubmed/37024481
http://dx.doi.org/10.1038/s41536-023-00294-3