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The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway
When the proliferation of residual hepatocytes is prohibited, biliary epithelial cells (BECs) transdifferentiate into nascent hepatocytes to accomplish liver regeneration. Despite significant interest in transdifferentiation, little is known about the maintenance of nascent hepatocytes in post-injur...
Autores principales: | Song, Jingmei, Ma, Jianlong, Liu, Xing, Huang, Zhuofu, Li, Lianghui, Li, Linke, Luo, Lingfei, Ni, Rui, He, Jianbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079969/ https://www.ncbi.nlm.nih.gov/pubmed/37024481 http://dx.doi.org/10.1038/s41536-023-00294-3 |
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