Immune profiles according to EGFR mutant subtypes and correlation with PD-1/PD-L1 inhibitor therapies in lung adenocarcinoma

BACKGROUND: We examined the distributions of 22 immune cell types and the responses to PD-1/PD-L1 inhibitors according to EGFR mutation profile, in three independent datasets of lung adenocarcinoma (LUAD). METHODS: We used CIBERSORTx to analyze the distributions of immune cells, and tumor immune dys...

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Detalles Bibliográficos
Autores principales: Koh, Young Wha, Park, Bumhee, Jung, Se Hee, Han, Jae-Ho, Haam, Seokjin, Lee, Hyun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079979/
https://www.ncbi.nlm.nih.gov/pubmed/37033978
http://dx.doi.org/10.3389/fimmu.2023.1137880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079979/
https://www.ncbi.nlm.nih.gov/pubmed/37033978
http://dx.doi.org/10.3389/fimmu.2023.1137880

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