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Targeting dormant phenotype acquired mycobacteria using natural products by exploring its important targets: In vitro and in silico studies

The dormant phenotype of Mycobacterium tuberculosis that develops during infection poses a major challenge in disease treatment, since these bacilli show tolerance to front-line drugs. An in vitro hypoxia dormancy model was established, which produced phenotypically dormant Mycobacterium smegmatis a...

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Detalles Bibliográficos
Autores principales: Sharma, Shweta, Chikhale, Rupesh, Shinde, Nivedita, Khan, A. M., Gupta, Vivek Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080046/
https://www.ncbi.nlm.nih.gov/pubmed/37033483
http://dx.doi.org/10.3389/fcimb.2023.1111997