Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors

BACKGROUND: Medulloblastoma, the most common malignant pediatric brain tumor, displays marked sex differences in prevalence of the four main molecular subgroups: SHH, WNT, Group 3 and Group 4. Males are more frequently diagnosed with SHH, Group 3 and 4 tumors, which have worse prognoses than WNT tum...

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Detalles Bibliográficos
Autores principales: Moss, Rachel M., Sorajja, Natali, Mills, Lauren J., Moertel, Christopher L., Hoang, Thanh T., Spector, Logan G., Largaespada, David A., Williams, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080161/
https://www.ncbi.nlm.nih.gov/pubmed/37035203
http://dx.doi.org/10.3389/fonc.2023.1113121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080161/
https://www.ncbi.nlm.nih.gov/pubmed/37035203
http://dx.doi.org/10.3389/fonc.2023.1113121

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