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Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors
BACKGROUND: Medulloblastoma, the most common malignant pediatric brain tumor, displays marked sex differences in prevalence of the four main molecular subgroups: SHH, WNT, Group 3 and Group 4. Males are more frequently diagnosed with SHH, Group 3 and 4 tumors, which have worse prognoses than WNT tum...
Autores principales: | Moss, Rachel M., Sorajja, Natali, Mills, Lauren J., Moertel, Christopher L., Hoang, Thanh T., Spector, Logan G., Largaespada, David A., Williams, Lindsay A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080161/ https://www.ncbi.nlm.nih.gov/pubmed/37035203 http://dx.doi.org/10.3389/fonc.2023.1113121 |
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