Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model

The development of an effective and durable vaccine remains a central goal in the fight against malaria. Circumsporozoite protein (CSP) is the major surface protein of sporozoites and the target of the only licensed Plasmodium falciparum (Pf) malaria vaccine, RTS,S/AS01. However, vaccine efficacy is...

Descripción completa

Detalles Bibliográficos
Autores principales: Ludwig, Julia, Scally, Stephen W., Costa, Giulia, Hoffmann, Sandro, Murugan, Rajagopal, Lossin, Jana, Prieto, Katherine, Obraztsova, Anna, Lobeto, Nina, Franke-Fayard, Blandine, Janse, Chris J., Lebas, Celia, Collin, Nicolas, Binter, Spela, Kellam, Paul, Levashina, Elena A., Wardemann, Hedda, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080175/
https://www.ncbi.nlm.nih.gov/pubmed/37029167
http://dx.doi.org/10.1038/s41541-023-00653-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080175/
https://www.ncbi.nlm.nih.gov/pubmed/37029167
http://dx.doi.org/10.1038/s41541-023-00653-7

Ejemplares similares