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Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model

The development of an effective and durable vaccine remains a central goal in the fight against malaria. Circumsporozoite protein (CSP) is the major surface protein of sporozoites and the target of the only licensed Plasmodium falciparum (Pf) malaria vaccine, RTS,S/AS01. However, vaccine efficacy is...

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Detalles Bibliográficos
Autores principales:	Ludwig, Julia, Scally, Stephen W., Costa, Giulia, Hoffmann, Sandro, Murugan, Rajagopal, Lossin, Jana, Prieto, Katherine, Obraztsova, Anna, Lobeto, Nina, Franke-Fayard, Blandine, Janse, Chris J., Lebas, Celia, Collin, Nicolas, Binter, Spela, Kellam, Paul, Levashina, Elena A., Wardemann, Hedda, Julien, Jean-Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080175/ https://www.ncbi.nlm.nih.gov/pubmed/37029167 http://dx.doi.org/10.1038/s41541-023-00653-7

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