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Immune landscape and the key role of APOE+ monocytes of lupus nephritis under the single‐cell and spatial transcriptional vista

BACKGROUND: Lupus nephritis (LN) is among the most common complication of systemic lupus erythematosus (SLE) with high mortality and morbidity. The analysis of LN kidney's local immune response through single‐cell and spatial transcriptome enables the study of potential therapeutic targets. MET...

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Detalles Bibliográficos
Autores principales: Tang, Youzhou, Zhang, Ying, Li, Xinyu, Xu, Ruoyao, Ji, Ying, Liu, Jishi, Liu, Jianye, Zhuang, Quan, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080215/
https://www.ncbi.nlm.nih.gov/pubmed/37026377
http://dx.doi.org/10.1002/ctm2.1237