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Overexpression of SPHK1 associated with targeted therapy resistance in predicting poor prognosis in renal cell carcinoma
BACKGROUND: Sphingosine kinase 1 (SPHK1) is a key enzyme that catalyzes the phosphorylation of sphingosine. Recent studies reported SPHK1 to be associated with renal cell carcinoma (RCC) progression by inducing targeted therapy resistance. However, the expression and the clinical significance of SPH...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080319/ https://www.ncbi.nlm.nih.gov/pubmed/37033345 http://dx.doi.org/10.21037/tcr-22-417 |