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Overexpression of SPHK1 associated with targeted therapy resistance in predicting poor prognosis in renal cell carcinoma

BACKGROUND: Sphingosine kinase 1 (SPHK1) is a key enzyme that catalyzes the phosphorylation of sphingosine. Recent studies reported SPHK1 to be associated with renal cell carcinoma (RCC) progression by inducing targeted therapy resistance. However, the expression and the clinical significance of SPH...

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Detalles Bibliográficos
Autores principales:	Bao, Ji-Ming, Zhi, Xi, Yuan, Hao-Yu, Chen, Tao-Yi, Chen, Ming-Kun, Zhou, Jun-Hao, Xue, Kang-Yi, Yang, Jian-Kun, Liu, Cun-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080319/ https://www.ncbi.nlm.nih.gov/pubmed/37033345 http://dx.doi.org/10.21037/tcr-22-417

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