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PAK4-relevant proliferation reduced by cell autophagy via p53/mTOR/p-AKT signaling

BACKGROUND: P21-activated kinase 4 (PAK4) involves in cell proliferation in cancer and mutually regulates with p53, a molecule is demonstrated to control cell autophagy by mammalian target of rapamycin (mTOR)/protein kinase B (AKT) signaling. Since the signaling exhibits an association with PAK fami...

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Detalles Bibliográficos
Autores principales: Li, Qing, Wang, Su-Jie, Wang, Wen-Jia, Ye, Yu-Cai, Ling, Ya-Qin, Dai, Ya-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080326/
https://www.ncbi.nlm.nih.gov/pubmed/37033362
http://dx.doi.org/10.21037/tcr-22-2272