The therapeutic effect and mechanism of parthenolide in skeletal disease, cancers, and cytokine storm

Parthenolide (PTL or PAR) was first isolated from Magnolia grandiflora and identified as a small molecule cancer inhibitor. PTL has the chemical structure of C15H20O3 with characteristics of sesquiterpene lactones and exhibits the biological property of inhibiting DNA biosynthesis of cancer cells. I...

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Detalles Bibliográficos
Autores principales: Zhu, Sipin, Sun, Ping, Bennett, Samuel, Charlesworth, Oscar, Tan, Renxiang, Peng, Xing, Gu, Qiang, Kujan, Omar, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080395/
https://www.ncbi.nlm.nih.gov/pubmed/37033622
http://dx.doi.org/10.3389/fphar.2023.1111218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080395/
https://www.ncbi.nlm.nih.gov/pubmed/37033622
http://dx.doi.org/10.3389/fphar.2023.1111218

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