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The therapeutic effect and mechanism of parthenolide in skeletal disease, cancers, and cytokine storm

Parthenolide (PTL or PAR) was first isolated from Magnolia grandiflora and identified as a small molecule cancer inhibitor. PTL has the chemical structure of C15H20O3 with characteristics of sesquiterpene lactones and exhibits the biological property of inhibiting DNA biosynthesis of cancer cells. I...

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Detalles Bibliográficos
Autores principales:	Zhu, Sipin, Sun, Ping, Bennett, Samuel, Charlesworth, Oscar, Tan, Renxiang, Peng, Xing, Gu, Qiang, Kujan, Omar, Xu, Jiake
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080395/ https://www.ncbi.nlm.nih.gov/pubmed/37033622 http://dx.doi.org/10.3389/fphar.2023.1111218

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