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Scientific rationale for the use of α2A-adrenoceptor agonists in treating neuroinflammatory cognitive disorders

Neuroinflammatory disorders preferentially impair the higher cognitive and executive functions of the prefrontal cortex (PFC). This includes such challenging disorders as delirium, perioperative neurocognitive disorder, and the sustained cognitive deficits from “long-COVID” or traumatic brain injury...

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Detalles Bibliográficos
Autores principales: Arnsten, Amy F. T., Ishizawa, Yumiko, Xie, Zhongcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080530/
https://www.ncbi.nlm.nih.gov/pubmed/37029295
http://dx.doi.org/10.1038/s41380-023-02057-4