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Recent advances in therapeutic CRISPR-Cas9 genome editing: mechanisms and applications
Recently, clustered regularly interspaced palindromic repeats (CRISPR)-Cas9 derived editing tools had significantly improved our ability to make desired changes in the genome. Wild-type Cas9 protein recognizes the target genomic loci and induced local double strand breaks (DSBs) in the guidance of s...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Nature Singapore
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080534/ https://www.ncbi.nlm.nih.gov/pubmed/37027099 http://dx.doi.org/10.1186/s43556-023-00115-5 |