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Intraneuronal tau aggregation induces the integrated stress response in astrocytes

Progressive aggregation of tau protein in neurons is associated with neurodegeneration in tauopathies. Cell non-autonomous disease mechanisms in astrocytes may be important drivers of the disease process but remain largely elusive. Here, we studied cell type-specific responses to intraneuronal tau a...

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Detalles Bibliográficos
Autores principales: Batenburg, Kevin L, Kasri, Nael N, Heine, Vivi M, Scheper, Wiep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080549/
https://www.ncbi.nlm.nih.gov/pubmed/36520068
http://dx.doi.org/10.1093/jmcb/mjac071