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Intraneuronal tau aggregation induces the integrated stress response in astrocytes
Progressive aggregation of tau protein in neurons is associated with neurodegeneration in tauopathies. Cell non-autonomous disease mechanisms in astrocytes may be important drivers of the disease process but remain largely elusive. Here, we studied cell type-specific responses to intraneuronal tau a...
Autores principales: | Batenburg, Kevin L, Kasri, Nael N, Heine, Vivi M, Scheper, Wiep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080549/ https://www.ncbi.nlm.nih.gov/pubmed/36520068 http://dx.doi.org/10.1093/jmcb/mjac071 |
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