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Conformational Selection of a Tryptophan Side Chain Drives the Generalized Increase in Activity of PET Hydrolases through a Ser/Ile Double Mutation

[Image: see text] Poly(ethylene terephthalate) (PET) is the most common polyester plastic in the packaging industry and a major source of environmental pollution due to its single use. Several enzymes, termed PET hydrolases, have been found to hydrolyze this polymer at different temperatures, with t...

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Detalles Bibliográficos
Autores principales: Crnjar, Alessandro, Griñen, Aransa, Kamerlin, Shina C. L., Ramírez-Sarmiento, César A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080609/
https://www.ncbi.nlm.nih.gov/pubmed/37035283
http://dx.doi.org/10.1021/acsorginorgau.2c00054