Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress

[Image: see text] Increased ATP release and its extracellular catabolism through CD73 (ecto-5′-nucleotidase) lead to the overactivation of adenosine A(2A) receptors (A(2A)R), which occurs in different brain disorders. A(2A)R blockade blunts mood and memory dysfunction caused by repeated stress, but...

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Detalles Bibliográficos
Autores principales: Dias, Liliana, Pochmann, Daniela, Lemos, Cristina, Silva, Henrique B., Real, Joana I., Gonçalves, Francisco Q., Rial, Daniel, Gonçalves, Nélio, Simões, Ana Patrícia, Ferreira, Samira G., Agostinho, Paula, Cunha, Rodrigo A., Tomé, Angelo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080657/
https://www.ncbi.nlm.nih.gov/pubmed/36881648
http://dx.doi.org/10.1021/acschemneuro.2c00810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080657/
https://www.ncbi.nlm.nih.gov/pubmed/36881648
http://dx.doi.org/10.1021/acschemneuro.2c00810

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