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Leptin ameliorates Aβ1-42-induced Alzheimer’s disease by suppressing inflammation via activating p-Akt signaling pathway

BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive neuronal loss, cognitive disorder, and memory decline. Leptin has been reported to have a neuroprotective effect on neurodegenerative diseases. OBJECTIVE: Our aim was to investigate whether intraperitoneal injection of leptin has a...

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Detalhes bibliográficos
Autores principales: Lu, Lin, Fu, Zijuan, Wu, Bing, Zhang, Dongsen, Wang, Ying
Formato: Online Artigo Texto
Idioma:English
Publicado em: De Gruyter 2023
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080705/
https://www.ncbi.nlm.nih.gov/pubmed/37035120
http://dx.doi.org/10.1515/tnsci-2022-0270