AG1024, an IGF-1 receptor inhibitor, ameliorates renal injury in rats with diabetic nephropathy via the SOCS/JAK2/STAT pathway

Insulin-like-growth factor-1 (IGF-1) is the ligand for insulin-like growth factor-1 receptor (IGF-1R), and the roles of IGF-1/IGF-1R in diabetic nephropathy (DN) are well-characterized previously. However, the biological functions of AG1024 (an IGF-1R inhibitor) in DN remain unknown. This study inve...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jianhua, Zhang, Yun, Liu, Min, Shi, Feng, Cheng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080708/
https://www.ncbi.nlm.nih.gov/pubmed/37034500
http://dx.doi.org/10.1515/med-2023-0683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080708/
https://www.ncbi.nlm.nih.gov/pubmed/37034500
http://dx.doi.org/10.1515/med-2023-0683

Ejemplares similares