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Exendin-4 regulates the MAPK and WNT signaling pathways to alleviate the osteogenic inhibition of periodontal ligament stem cells in a high glucose environment

Diabetes mellitus (DM) increases the destruction of periodontal tissue and impairs osteogenesis differentiation. Exendin-4 (Ex-4), a glucagon-like peptide-1 (GLP-1) analogue, can be used for treating DM and promotes bone regeneration. The aim of this study was to explore the effect and mechanism of...

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Detalles Bibliográficos
Autores principales: Wang, Min, Liu, Min, Zheng, Jiawen, Xiong, Li, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080709/
https://www.ncbi.nlm.nih.gov/pubmed/37034502
http://dx.doi.org/10.1515/med-2023-0692