SARS-CoV-2 evolved variants optimize binding to cellular glycocalyx

Viral variants of concern continue to arise for SARS-CoV-2, potentially impacting both methods for detection and mechanisms of action. Here, we investigate the effect of an evolving spike positive charge in SARS-CoV-2 variants and subsequent interactions with heparan sulfate and the angiotensin conv...

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Detalles Bibliográficos
Autores principales: Kim, Sang Hoon, Kearns, Fiona L., Rosenfeld, Mia A., Votapka, Lane, Casalino, Lorenzo, Papanikolas, Micah, Amaro, Rommie E., Freeman, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080732/
https://www.ncbi.nlm.nih.gov/pubmed/37077408
http://dx.doi.org/10.1016/j.xcrp.2023.101346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080732/
https://www.ncbi.nlm.nih.gov/pubmed/37077408
http://dx.doi.org/10.1016/j.xcrp.2023.101346

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