Transcriptomics and metabolomics analysis of L-phenylalanine overproduction in Escherichia coli

BACKGROUND: Highly efficient production of L-phenylalanine (L-Phe) in E. coli has been achieved by multiple rounds of random mutagenesis and modification of key genes of the shikimate (SHIK) and L-Phe branch pathways. In this study, we performed transcriptomic (16, 24 and 48 h) and metabolomic analy...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Ding, Dongqin, Bai, Danyang, Lin, Yang, Zhu, Yaru, Zhang, Cuiying, Zhang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080781/
https://www.ncbi.nlm.nih.gov/pubmed/37024921
http://dx.doi.org/10.1186/s12934-023-02070-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080781/
https://www.ncbi.nlm.nih.gov/pubmed/37024921
http://dx.doi.org/10.1186/s12934-023-02070-w

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