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CaCO(3) powder-mediated biomineralization of antigen nanosponges synergize with PD-1 blockade to potentiate anti-tumor immunity

Antigen self-assembly nanovaccines advance the minimalist design of therapeutic cancer vaccines, but the issue of inefficient cross-presentation has not yet been fully addressed. Herein, we report a unique approach by combining the concepts of “antigen multi-copy display” and “calcium carbonate (CaC...

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Detalles Bibliográficos
Autores principales: Su, Runping, Gu, Jingjing, Sun, Juanjuan, Zang, Jie, Zhao, Yuge, Zhang, Tingting, Chen, Yingna, Chong, Gaowei, Yin, Weimin, Zheng, Xiao, Liu, Bingbing, Huang, Li, Ruan, Shuangrong, Dong, Haiqing, Li, Yan, Li, Yongyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080855/
https://www.ncbi.nlm.nih.gov/pubmed/37024939
http://dx.doi.org/10.1186/s12951-023-01870-x