Microfluidic Platforms Promote Polarization of Human-Derived Retinal Ganglion Cells That Model Axonopathy

PURPOSE: Axons depend on long-range transport of proteins and organelles which increases susceptibility to metabolic stress in disease. The axon initial segment (AIS) is particularly vulnerable due to the high bioenergetic demand of action potential generation. Here, we prepared retinal ganglion cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Boal, Andrew M., McGrady, Nolan R., Chamling, Xitiz, Kagitapalli, Bhanu S., Zack, Donald J., Calkins, David J., Risner, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080917/
https://www.ncbi.nlm.nih.gov/pubmed/37010860
http://dx.doi.org/10.1167/tvst.12.4.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080917/
https://www.ncbi.nlm.nih.gov/pubmed/37010860
http://dx.doi.org/10.1167/tvst.12.4.1

Ejemplares similares